| Date | Opponent | C-N Game Notes |
|---|---|---|
| Nov. 13, 2021 | #3 Lander | C-N Game Notes |
| Nov. 14, 2021 | USC Aiken | C-N Game Notes |
| Nov. 17, 2021 | at Tusculum | C-N Game Notes |
| Nov. 20, 2021 | Queens | C-N Game Notes |
| Nov. 23, 2021 | at Clayton State | C-N Game Notes |
| Nov. 27, 2021 | Wingate | C-N Game Notes |
| Dec. 1, 2021 | Lenoir-Rhyne | C-N Game Notes |
| Dec. 4, 2021 | Anderson | C-N Game Notes |
| Dec. 8, 2021 | at UVA Wise | C-N Game Notes |
| Dec. 11, 2021 | at Newberry | C-N Game Notes |
| Dec. 15, 2021 | Mars Hill | C-N Game Notes |
| Dec. 18, 2021 | at Limestone | C-N Game Notes |
| Jan. 5, 2022 | UVA Wise | C-N Game Notes |
| Jan. 8, 2022 | at Anderson | C-N Game Notes |
| Jan. 12, 2022 | at #21 Catawba | C-N Game Notes |
| Jan. 15, 2022 | at Lenoir-Rhyne | C-N Game Notes |
| Jan. 17, 2022 | Coker | C-N Game Notes |
| Jan. 19, 2022 | Emory & Henry | C-N Game Notes |
| Jan. 22, 2022 | at #17 Wingate | C-N Game Notes |
| Jan. 26, 2022 | at Lincoln Memorial | C-N Game Notes |
| Jan. 29, 2022 | Newberry | C-N Game Notes |
| Feb. 2, 2022 | Tusculum | C-N Game Notes |
| Feb. 12, 2022 | #14 Catawba | C-N Game Notes |
| Feb. 14, 2022 | at Queens | C-N Game Notes |
| Feb. 16, 2022 | at Mars Hill | C-N Game Notes |
| Feb. 19, 2022 | Limestone | C-N Game Notes |
| Feb. 23, 2022 | Lincoln Memorial | C-N Game Notes |
| Feb. 26, 2022 | at Coker | C-N Game Notes |
| March 2, 2022 |
#7 UVA Wise |
C-N Game Notes |
| March 5, 2022 |
#3 Catawba |
C-N Game Notes |
| March 11, 2022 |
#4 Wingate |
C-N Game Notes |